Hjv^tm2Nca
Targeted Allele Detail

Summary

• Symbol: Hjv^tm2Nca
• Name: hemojuvelin BMP co-receptor; targeted mutation 2, Nancy C Andrews
• MGI ID: MGI:5141508
• Synonyms: Hjv fl
• Gene: Hjv Location: Chr3:96432488-96436526 bp, + strand Genetic Position: Chr3, 41.91 cM
• Alliance: Hjv^tm2Nca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174702
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 4. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 4. (J:174702)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hjv Mutation: 19 strains or lines available

References

• Original: J:174702 Chen W, et al., Skeletal muscle hemojuvelin is dispensable for systemic iron homeostasis. Blood. 2011 Jun 9;117(23):6319-25
• All: 3 reference(s)