Arhgap15^tm1Ehi
Targeted Allele Detail

Summary

• Symbol: Arhgap15^tm1Ehi
• Name: Rho GTPase activating protein 15; targeted mutation 1, Emilio Hirsch
• MGI ID: MGI:5142283
• Gene: Arhgap15 Location: Chr2:43638836-44285965 bp, + strand Genetic Position: Chr2, 26.13 cM
• Alliance: Arhgap15^tm1Ehi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174896
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a lacZ and a neomycin resistance cassette in the ATG start site in exon 1. (J:174896)

Expression

In Mice Carrying this Mutation:

106 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap15 Mutation: 30 strains or lines available

References

• Original: J:174896 Costa C, et al., The RacGAP ArhGAP15 is a master negative regulator of neutrophil functions. Blood. 2011 Jul 28;118(4):1099-108
• All: 5 reference(s)