Il33^{Gt(IST10946B6)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Il33^{Gt(IST10946B6)Tigm}
• Name: interleukin 33; gene trap IST10946B6, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5146687
• Synonyms: Il-33^Gt, Il-33^{Gt(IST10946B6-Tigm)Girard}
• Gene: Il33 Location: Chr19:29902514-29938118 bp, + strand Genetic Position: Chr19, 24.56 cM, cytoband C2
• Alliance: Il33^{Gt(IST10946B6)Tigm} page

Mutation origin

• Mutant Cell Line: IST10946B6
• Germline Transmission: Earliest citation of germline transmission: J:183103
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap vector inserted upstream of exon 2. Western blot analysis confirmed the absence of protein expression in the lungs. (J:183103)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST10946B6HMR1	JM184773 ; (MGI Seq Detail)	inverse PCR	Chr19:29923994-29924343 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Il33 Mutation: 33 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 30 reference(s)