Tnfaip8^{Gt(IST13629C1)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Tnfaip8^{Gt(IST13629C1)Tigm}
• Name: tumor necrosis factor, alpha-induced protein 8; gene trap IST13629C1, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5178061
• Gene: Tnfaip8 Location: Chr18:50112494-50226296 bp, + strand Genetic Position: Chr18, 27.18 cM
• Alliance: Tnfaip8^{Gt(IST13629C1)Tigm} page

Mutation origin

• Mutant Cell Line: IST13629C1
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap inserted between exons 1 and 4. RT-PCR confirmed the absence of full-length transcript expression in the brain, spinal cord, heart, lung, thymus, spleen, kidney and liver. (J:223320)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST13629C1BBF1	JM242544 ; (MGI Seq Detail)	inverse PCR	Chr18:50218293-50218535 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  21 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Tnfaip8 Mutation: 18 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 11 reference(s)