Mmp25^{Gt(IST14198E10)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Mmp25^{Gt(IST14198E10)Tigm}
• Name: matrix metallopeptidase 25; gene trap IST14198E10, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5212225
• Gene: Mmp25 Location: Chr17:23847289-23864243 bp, - strand Genetic Position: Chr17, 11.87 cM
• Alliance: Mmp25^{Gt(IST14198E10)Tigm} page

Mutation origin

• Mutant Cell Line: IST14198E10
• Germline Transmission: Earliest citation of germline transmission: J:347009
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap cassette inserted between exons 1 and 2. Quantitative RT-PCR confirmed the absence of mRNA expression in bone marrow, lung, and spleen from homozygous mice. (J:347009)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST14198E10BBF1	JM290089 ; (MGI Seq Detail)	inverse PCR	Chr17:23862552-23862889 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Mmp25 Mutation: 32 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)