Upf3b^{Gt(IST14619B5)Tigm}
Gene trapped Allele Detail

Summary

• Symbol: Upf3b^{Gt(IST14619B5)Tigm}
• Name: UPF3 regulator of nonsense transcripts homolog B (yeast); gene trap IST14619B5, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:5248632
• Gene: Upf3b Location: ChrX:36355331-36373975 bp, - strand Genetic Position: ChrX, 21.51 cM, cytoband A2
• Alliance: Upf3b^{Gt(IST14619B5)Tigm} page

Mutation origin

• Mutant Cell Line: IST14619B5
• Germline Transmission: Earliest citation of germline transmission: J:222866
• Parent Cell Line: Lex3.13 (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: The gene trap cassette inserted in intron 1. mRNA levels were decreased by over 100-fold in most tissues. Western blot analysis failed to detect protein in brains from homozygous mice.
• Sequence Tags: Sequence tag details (3 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  IST14619B5HMF1	JM342678 ; (MGI Seq Detail)	inverse PCR	ChrX:36373407-36373886 bp (-)
  IST14619B5BBF1	JM342677 ; (MGI Seq Detail)	inverse PCR	ChrX:36373407-36373856 bp (-)
  IST14619B5HMR1	JM342679 ; (MGI Seq Detail)	inverse PCR	ChrX:36372974-36373408 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Upf3b Mutation: 13 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)