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Adam17tm1Rain
Targeted Allele Detail
Summary
Symbol: Adam17tm1Rain
Name: a disintegrin and metallopeptidase domain 17; targeted mutation 1, Elaine Raines
MGI ID: MGI:5284875
Synonyms: Adam17deltaEx5
Gene: Adam17  Location: Chr12:21373510-21423633 bp, - strand  Genetic Position: Chr12, 8.3 cM
Alliance: Adam17tm1Rain page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:174865
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 5 was deleted. (J:174865)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adam17 Mutation:  64 strains or lines available
References
Original:  J:174865 Tang J, et al., Adam17-dependent shedding limits early neutrophil influx but does not alter early monocyte recruitment to inflammatory sites. Blood. 2011 Jul 21;118(3):786-94
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory