Cacng4^tm1Ran
Targeted Allele Detail

Summary

• Symbol: Cacng4^tm1Ran
• Name: calcium channel, voltage-dependent, gamma subunit 4; targeted mutation 1, Roger A Nicoll
• MGI ID: MGI:5285084
• Synonyms: gamma 4, Tarp gamma 4
• Gene: Cacng4 Location: Chr11:107623183-107685383 bp, - strand Genetic Position: Chr11, 70.29 cM, cytoband E1
• Alliance: Cacng4^tm1Ran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175164
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a neomycin resistance cassette. Western blot analysis confirmed the absence of protein product. (J:175164)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cacng4 Mutation: 15 strains or lines available

References

• Original: J:175164 Milstein AD, et al., TARP subtypes differentially and dose-dependently control synaptic AMPA receptor gating. Neuron. 2007 Sep 20;55(6):905-18
• All: 2 reference(s)