Rr104^tm1.1Mym
Targeted Allele Detail

Summary

• Symbol: Rr104^tm1.1Mym
• Name: regulatory region 104; targeted mutation 1.1, Masayuki Yamamoto
• MGI ID: MGI:5285264
• Synonyms: Epo^f, Epo^tm1.1Mym
• Gene: Rr104 Location: unknown Genetic Position: Chr5, Syntenic
• Alliance: Rr104^tm1.1Mym page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175070
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Modified regulatory region, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: An IRES, the GFP gene and a loxP site were inserted into the 3' UTR and a loxP site flanked neomycin resistance gene cassette was inserted downstream of a 0.5 kb genomic fragment containing the EpoE-3' enhancer region. Cre-mediated recombination removed the neo cassette. (J:175070)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr104 Mutation: 0 strains or lines available

References

• Original: J:175070 Suzuki N, et al., Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages. Mol Cell Biol. 2011 Sep;31(18):3896-905
• All: 1 reference(s)