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Rr104tm1.2Mym
Targeted Allele Detail
Summary
Symbol: Rr104tm1.2Mym
Name: regulatory region 104; targeted mutation 1.2, Masayuki Yamamoto
MGI ID: MGI:5285265
Synonyms: Epodelta, Epodelta3'E, Epotm1.2Mym
Gene: Rr104  Location: unknown  Genetic Position: Chr5, Syntenic
Alliance: Rr104tm1.2Mym page
The snout and paws of Rr104tm1.2Mym/Rr104tm1.2Mym Tg(Epo*)458Mym/0 (ISAM) mice are whiter than those of controls

Show the 3 phenotype image(s) involving this allele.

Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:175070
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Modified regulatory region, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAn IRES, the GFP gene and a loxP site were inserted into the 3' UTR and a loxP site flanked neomycin resistance gene cassette was inserted downstream of a 0.5 kb genomic fragment containing the EpoE-3' enhancer region. Cre-mediated recombination removed the neo cassette and the enhancer region and part of the 3' UTR. (J:175070)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr104 Mutation:  0 strains or lines available
References
Original:  J:175070 Suzuki N, et al., Specific contribution of the erythropoietin gene 3' enhancer to hepatic erythropoiesis after late embryonic stages. Mol Cell Biol. 2011 Sep;31(18):3896-905
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory