Tg(POU3F4-cre)M51Cren
Transgene Detail

Summary

• Symbol: Tg(POU3F4-cre)M51Cren
• Name: transgene insertion M51, Bryan Crenshaw III
• MGI ID: MGI:5285402
• Synonyms: M51
• Transgene: Tg(POU3F4-cre)M51Cren Location: unknown
• Alliance: Tg(POU3F4-cre)M51Cren page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(POU3F4-cre)M51Cren expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  human

  POU3F4 (5456)

  Pou3f4

  (MGI:101894)

• Mutation details: The 3.6 kb otic enhancer region of the human POU3F4 gene was fused to the herpes thymidine kinase promoter to drive expression of cre recombinase. Nine founders were obtained, with 6 displaying expression in the otic mesenchyme, including line M51 which had the highest expression level. (J:146839)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	POU3F4 (human) Summary of all recombinase alleles driven by POU3F4. Comparative matrix view of recombinase activities Alliance human POU3F4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:146839 Ahn KJ, et al., Otic mesenchyme expression of Cre recombinase directed by the inner ear enhancer of the Brn4/Pou3f4 gene. Genesis. 2009 Mar;47(3):137-41
• All: 2 reference(s)