Dnm3^tm1.2Pdc
Targeted Allele Detail

Summary

• Symbol: Dnm3^tm1.2Pdc
• Name: dynamin 3; targeted mutation 1.2, Pietro De Camilli
• MGI ID: MGI:5285526
• Gene: Dnm3 Location: Chr1:161810022-162305603 bp, - strand Genetic Position: Chr1, 69.95 cM
• Alliance: Dnm3^tm1.2Pdc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175247
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/Sv and C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 2 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on brain, testis, and lung extracts. (J:175247)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dnm3 Mutation: 63 strains or lines available

References

• Original: J:175247 Raimondi A, et al., Overlapping role of dynamin isoforms in synaptic vesicle endocytosis. Neuron. 2011 Jun 23;70(6):1100-14
• All: 6 reference(s)