Stc2^tm1Gthi
Targeted Allele Detail

Summary

• Symbol: Stc2^tm1Gthi
• Name: stanniocalcin 2; targeted mutation 1, Gopal Thinakaran
• MGI ID: MGI:5285561
• Gene: Stc2 Location: Chr11:31309441-31320061 bp, - strand Genetic Position: Chr11, 18.4 cM
• Alliance: Stc2^tm1Gthi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175075
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence of exons 1 and 2 were replaced with a lacZ/neo cassette. The absence of transcript expression was confirmed by western blot analysis in kidney extract. (J:175075)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stc2 Mutation: 21 strains or lines available

References

• Original: J:175075 Zeiger W, et al., Stanniocalcin 2 is a negative modulator of store-operated calcium entry. Mol Cell Biol. 2011 Sep;31(18):3710-22
• All: 1 reference(s)