H2-Ab1^b-tm1.1Koni
Targeted Allele Detail

Summary

• Symbol: H2-Ab1^b-tm1.1Koni
• Name: histocompatibility 2, class II antigen A, beta 1; targeted mutation 1.1, Pandelakis A Koni
• MGI ID: MGI:5285594
• Synonyms: H2-Ab1^tm1.1Koni
• Gene: H2-Ab1 Location: Chr17:34482201-34488392 bp, + strand Genetic Position: Chr17, 17.98 cM
• Alliance: H2-Ab1^b-tm1.1Koni page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131774
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 1. (J:131774)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any H2-Ab1 Mutation: 83 strains or lines available

References

• Original: J:131774 Shimoda M, et al., Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance. J Immunol. 2006 Jun 1;176(11):6503-11
• All: 1 reference(s)