Rbm3^tm1Ttg
Targeted Allele Detail

Summary

• Symbol: Rbm3^tm1Ttg
• Name: RNA binding motif (RNP1, RRM) protein 3; targeted mutation 1, Tadatsugu Taniguchi
• MGI ID: MGI:5285686
• Gene: Rbm3 Location: ChrX:8005214-8012119 bp, - strand Genetic Position: ChrX, 3.68 cM
• Alliance: Rbm3^tm1Ttg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174947
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 through 6 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:174947)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbm3 Mutation: 15 strains or lines available

References

• Original: J:174947 Matsuda A, et al., Generation of mice deficient in RNA-binding motif protein 3 (RBM3) and characterization of its role in innate immune responses and cell growth. Biochem Biophys Res Commun. 2011 Jul 22;411(1):7-13
• All: 5 reference(s)