Tsix^tm1.1Awu
Targeted Allele Detail

Summary

• Symbol: Tsix^tm1.1Awu
• Name: X (inactive)-specific transcript, opposite strand; targeted mutation 1.1, Anton Wutz
• MGI ID: MGI:5285833
• Synonyms: TT
• Gene: Tsix Location: ChrX:102475123-102528563 bp, + strand Genetic Position: ChrX, 46.13 cM
• Alliance: Tsix^tm1.1Awu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174672
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A Tet promoter was inserted 3.9 kb downstream from the major promoter. This insertion produces a tetracycline-regulated allele. Cre-mediated recombination removed the floxed puro cassette. (J:174672)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tsix Mutation: 57 strains or lines available

References

• Original: J:174672 Ohhata T, et al., Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice. Genes Dev. 2011 Aug 15;25(16):1702-15
• All: 1 reference(s)