Tg(Gfap-cre)#Mvs
Transgene Detail

Summary

• Symbol: Tg(Gfap-cre)#Mvs
• Name: transgene insertion, Michael V Sofroniew
• MGI ID: MGI:5285867
• Synonyms: mGFAP-Cre
• Transgene: Tg(Gfap-cre)#Mvs Location: unknown
• Alliance: Tg(Gfap-cre)#Mvs page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6NHsd)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gfap-cre)#Mvs expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gfap (MGI:95697)

• Mutation details: The bacterial Cre recombinase gene was inserted into the first exon of an expression cassette (clone 445) that contains all the introns, promoter regulatory elements, exons, and 2.5 kb of 5' and 2 kb of 3' flanking DNA of the astroglia-specific mouse glial fibrillary acidic protein gene. GFAP is not expressed from the transgene due to deletion of part of exon 1. Lines 73.12 and 77.6 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:94543)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gfap (mouse) Summary of all recombinase alleles driven by Gfap. Alliance mouse Gfap gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:174559 Amador-Arjona A, et al., Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory. J Neurosci. 2011 Jul 6;31(27):9933-44
• All: 16 reference(s)