Csn1s1^tm1Afk
Targeted Allele Detail

Summary

• Symbol: Csn1s1^tm1Afk
• Name: casein alpha s1; targeted mutation 1, Andreas F Kolb
• MGI ID: MGI:5285947
• Gene: Csn1s1 Location: Chr5:87814067-87830437 bp, + strand Genetic Position: Chr5, 43.56 cM
• Alliance: Csn1s1^tm1Afk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:174932
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A a pgk promoter driven hygromycin-thymidine kinase fusion gene replaced exon 2 and some of the surrounding genomic region via homologous recombination. (J:174932)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csn1s1 Mutation: 31 strains or lines available

References

• Original: J:174932 Kolb AF, et al., Milk lacking alpha-casein leads to permanent reduction in body size in mice. PLoS One. 2011;6(7):e21775
• All: 1 reference(s)