Tafa1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Tafa1^{tm1(KOMP)Vlcg}
• Name: TAFA chemokine like family member 1; targeted mutation 1, Velocigene
• MGI ID: MGI:5286469
• Synonyms: Fam19a1 KO
• Gene: Tafa1 Location: Chr6:96090135-96634159 bp, + strand Genetic Position: Chr6, 44.67 cM
• Alliance: Tafa1^{tm1(KOMP)Vlcg} page
• IMPC: Tafa1 gene page

Mutation origin

• Mutant Cell Lines: 16914A-E12, 16914A-F3, 16914A-F10, 16914A-G8
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 112bp between positions 96092621-96092732 of Chromosome 6 (Build GRCm39). Semi-quantitative PCR analysis confirmed the absence of mRNA transcript in the brain cortex of homozygous mutant mice. (J:136110, J:284736)

Expression

In Mice Carrying this Mutation:	128 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Tafa1 Mutation: 12 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 5 reference(s)