Cct3Tg(Tyr)2423AOve
Transgenic Allele Detail
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Symbol: |
Cct3Tg(Tyr)2423AOve |
Name: |
chaperonin containing TCP1 subunit 3; transgene lentiviral insertion 2423A, Paul A Overbeek |
MGI ID: |
MGI:5286663 |
Synonyms: |
OVE#2423A, OVE2423A |
Gene: |
Cct3 Location: Chr3:88204442-88229073 bp, + strand Genetic Position: Chr3, 38.79 cM, cytoband F
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Alliance: |
Cct3Tg(Tyr)2423AOve page
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Transgene Type: |
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Transgenic (Reporter) |
Mutation: |
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Insertion
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Mutation details: The Tyro-IRES-sd-loxP-FUGW lentiviral transgene (LV2187) was designed with a mouse tyrosinase minigene (Tyro) followed by an IRES::3xATG::splice-donor::loxP sequence in the FUGW self-inactivating HIV-based lentiviral vector backbone. The Tyro-IRES-sd-loxP replaced the ubiquitin-c promoter, EGFP, and WPRE sequences originally found in the FUGW lentiviral vector. The Tyro minigene is composed of the mouse Tyr enhancer region (623 bp), promoter region (657 bp), and 1566 bp cDNA sequence (including the stop codon); all in antisense orientation relative to the FUGW backbone. The Tyro minigene is followed by an internal ribosome entry site (IRES) ending with ATGs in all three reading frames (3xATG), an artificial splice donor sequence, and a loxP site in this construct. In line 2423A, the lentiviral transgene inserted into intron 10 (NCBI37/mm9; 3'-88,121,472(-)).
(J:175597)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cct3 Mutation: |
38 strains or lines available
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Original: |
J:175597 Overbeek PA, Direct Data Submission for Overbeek Lentiviral Transgenic Lines. MGI Direct Data Submission. 2011; |
All: |
1 reference(s) |
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