Mkx^tm1.2Jian
Targeted Allele Detail

Summary

• Symbol: Mkx^tm1.2Jian
• Name: mohawk homeobox; targeted mutation 1.2, Rulang Jiang
• MGI ID: MGI:5287572
• Synonyms: Mkx^-
• Gene: Mkx Location: Chr18:6934966-7004779 bp, - strand Genetic Position: Chr18, 4.53 cM
• Alliance: Mkx^tm1.2Jian page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175747
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 3 from Mkx^tm1.1Jian. (J:175747)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mkx Mutation: 28 strains or lines available

References

• Original: J:175747 Liu W, et al., The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807
• All: 2 reference(s)