2700049A03Rik^tm1.2Arte
Targeted Allele Detail

Summary

• Symbol: 2700049A03Rik^tm1.2Arte
• Name: RIKEN cDNA 2700049A03 gene; targeted mutation 1.2, TaconicArtemis
• MGI ID: MGI:5287585
• Synonyms: Talpid3^-
• Gene: 2700049A03Rik Location: Chr12:71183622-71290077 bp, + strand Genetic Position: Chr12, 29.39 cM, cytoband C3
• Alliance: 2700049A03Rik^tm1.2Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site and FRT flanked neo cassette were inserted upstream of exon 11 and a second loxP site was inserted downstream of exon 12 via homologous recombination. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed exons 11 and 12. (J:175541)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any 2700049A03Rik Mutation: 107 strains or lines available

References

• Original: J:175541 Bangs F, et al., Generation of mice with functional inactivation of talpid3, a gene first identified in chicken. Development. 2011 Aug;138(15):3261-72
• All: 2 reference(s)