Dcdc2a^tm1.1Jjlo
Targeted Allele Detail

Summary

• Symbol: Dcdc2a^tm1.1Jjlo
• Name: doublecortin domain containing 2a; targeted mutation 1.1, Joseph J LoTurco
• MGI ID: MGI:5288002
• Synonyms: Dcdc2^flox2
• Gene: Dcdc2a Location: Chr13:25239987-25394689 bp, + strand Genetic Position: Chr13, 10.89 cM
• Alliance: Dcdc2a^tm1.1Jjlo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175635
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed and an FRT flanked neo cassette was inserted via homologous recombination. Flp mediated recombination removed the neo cassette. (J:175635)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dcdc2a Mutation: 50 strains or lines available

References

• Original: J:175635 Wang Y, et al., Dcdc2 knockout mice display exacerbated developmental disruptions following knockdown of doublecortin. Neuroscience. 2011 Sep 8;190:398-408
• All: 2 reference(s)