Tg(KRT14-Kitl*)4XTG2Bjl
Transgene Detail

Summary

• Symbol: Tg(KRT14-Kitl*)4XTG2Bjl
• Name: transgene insertion 4XTG2, B Jack Longley
• MGI ID: MGI:5288393
• Synonyms: TG2
• Transgene: Tg(KRT14-Kitl*)4XTG2Bjl Location: unknown
• Alliance: Tg(KRT14-Kitl*)4XTG2Bjl page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Kitl*)4XTG2Bjl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Kitl (MGI:96974)

• Mutation details: The transgenic construct contains a mutant mouse Kitl (kit ligand) cDNA (deleting the primary high efficiency cleavage site between amino acids 164 and 165) under the control of the human keratin 14, KRT14, promoter. Founder line 4XTG2 was subsequently established. (J:113444)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:175889 Longley BJ, Creation of a transgenic mouse expressing mutated Kit ligand in the epidermis. MGI Direct Data Submission. 2011
• All: 11 reference(s)