Clic4^tm1.1Aidi
Targeted Allele Detail

Summary

• Symbol: Clic4^tm1.1Aidi
• Name: chloride intracellular channel 4; targeted mutation 1.1, Aihao Ding
• MGI ID: MGI:5288435
• Gene: Clic4 Location: Chr4:134941280-135000071 bp, - strand Genetic Position: Chr4, 67.19 cM, cytoband D3
• Alliance: Clic4^tm1.1Aidi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175404
• Parent Cell Line: CY2.4 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neo cassette with a 3' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exons 2 through 4 and the neo cassette. (J:175404)

Expression

In Mice Carrying this Mutation:	11 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Clic4 Mutation: 41 strains or lines available

References

• Original: J:175404 He G, et al., Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide. Eur J Immunol. 2011 May;41(5):1221-30
• All: 3 reference(s)