Mia2^cpto
Chemically induced Allele Detail

Summary

• Symbol: Mia2^cpto
• Name: MIA SH3 domain ER export factor 2; couch potato
• MGI ID: MGI:5290109
• Synonyms: Mia2^F91S
• Gene: Mia2 Location: Chr12:59142368-59237006 bp, + strand Genetic Position: Chr12, 26.0 cM
• Alliance: Mia2^cpto page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to C mutation that results in the amino acid substitution of serine for phenylalanine at position 91 (F91S). (J:176259)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mia2 Mutation: 31 strains or lines available

References

• Original: J:176259 Pitman JL, et al., Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites. J Lipid Res. 2011 Oct;52(10):1775-86
• All: 1 reference(s)