Tg(CAG-cre/Esr1*)67Csk
Transgene Detail

Summary

• Symbol: Tg(CAG-cre/Esr1*)67Csk
• Name: transgene insertion 67, Chugai Pharmaceutical Co, Ltd
• MGI ID: MGI:5291515
• Synonyms: Tg(CAG-MerCreMer)67Csk
• Transgene: Tg(CAG-cre/Esr1*)67Csk Location: unknown
• Alliance: Tg(CAG-cre/Esr1*)67Csk page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(CAG-cre/Esr1*)67Csk expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  chicken	CAG

• Mutation details: A transgene construct composed a sequence encoding a fusion of two copies of a mutated murine estrogen receptor and cre recombinase (cre/Esr1*) was microinjected into pronuclei of C57BL/6J oocytes. Line 67 was established. (J:173500)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	CAG (chicken) Summary of all recombinase alleles driven by CAG.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:173500 Tominaga T, et al., Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy. J Biol Chem. 2011 Jun 3;286(22):20109-16
• All: 2 reference(s)