Tg(Alx4-cre/ERT2)1Bky
Transgene Detail

Summary

• Symbol: Tg(Alx4-cre/ERT2)1Bky
• Name: transgene insertion 1, Bradley K Yoder
• MGI ID: MGI:5291907
• Synonyms: Alx4-CreER^T2, Gardener Mouse, Tg(Alx4-cre/ERT2)^GRD1Bky
• Transgene: Tg(Alx4-cre/ERT2)1Bky Location: unknown
• Alliance: Tg(Alx4-cre/ERT2)1Bky page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Alx4-cre/ERT2)1Bky expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Alx4 (MGI:108359)

• Mutation details: A 17kb promoter fragment of the mouse Alx4 (aristaless-like homeobox 4) was cloned upstream of the CreERT2 cDNA fusing Cre at codon 13 located within exon 2. This linear fragment was injected into pronuclei and chimeras were generated. The site of integration is unknown. (J:328710)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Alx4 (mouse) Summary of all recombinase alleles driven by Alx4. Comparative matrix view of recombinase activities Alliance mouse Alx4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:328710 Rockwell DM, et al., A transgenic Alx4-CreER mouse to analyze anterior limb and nephric duct development. Dev Dyn. 2022 Sep;251(9):1524-1534
• All: 1 reference(s)