Cox15^tm1.2Zev
Targeted Allele Detail

Summary

• Symbol: Cox15^tm1.2Zev
• Name: cytochrome c oxidase assembly protein 15; targeted mutation 1.2, Massimo Zeviani
• MGI ID: MGI:5292114
• Gene: Cox15 Location: Chr19:43721693-43741439 bp, - strand Genetic Position: Chr19, 36.67 cM
• Alliance: Cox15^tm1.2Zev page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176080
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 1 and 2. (J:176080)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cox15 Mutation: 27 strains or lines available

References

• Original: J:176080 Viscomi C, et al., In vivo correction of COX deficiency by activation of the AMPK/PGC-1alpha axis. Cell Metab. 2011 Jul 6;14(1):80-90
• All: 1 reference(s)