Rad21l^tm1Amp
Targeted Allele Detail

Summary

• Symbol: Rad21l^tm1Amp
• Name: RAD21-like (S. pombe); targeted mutation 1, Alberto M Pendas
• MGI ID: MGI:5292341
• Gene: Rad21l Location: Chr2:151487324-151510453 bp, - strand Genetic Position: Chr2, 74.83 cM
• Alliance: Rad21l^tm1Amp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176168
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Duplication, Insertion
• Rad21l^tm1Amp involves 1 genes/genome features (Rad21l) View all
• Mutation details: A targeting vector inserted Hprt and neo cassettes and duplicated exons 4 through 9. The absence of protein expression was confirmed by western blot analysis on testis extracts. (J:176168)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rad21l Mutation: 34 strains or lines available

References

• Original: J:176168 Herran Y, et al., The cohesin subunit RAD21L functions in meiotic synapsis and exhibits sexual dimorphism in fertility. EMBO J. 2011;30(15):3091-105
• All: 5 reference(s)