Tg(Avil-cre)1Phep
Transgene Detail

Summary

• Symbol: Tg(Avil-cre)1Phep
• Name: transgene insertion 1, Paul A Heppenstall
• MGI ID: MGI:5292346
• Synonyms: Advillin-Cre^tg
• Transgene: Tg(Avil-cre)1Phep Location: unknown
• Alliance: Tg(Avil-cre)1Phep page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Avil-cre)1Phep expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Avil (MGI:1333798)

• Mutation details: RedET recombineering was utilized to insert a cassette containing cre with a nuclear localization signal (NLS), a V5 epitope tag and the SV40 polyadenylation site, into a BAC clone (RP23-109K12) containing the advillin (Avil) locus. Correctly targeted clones were purified and injected into pronuclei of B6D2F1/N oocytes or prepared for intracytoplasmic sperm injection (ICSI). Both methods produced transgenic offspring. The line used for detailed analysis had 5 copies of the cre transgene. (J:176114)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Avil (mouse) Summary of all recombinase alleles driven by Avil. Comparative matrix view of recombinase activities Alliance mouse Avil gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:176114 Zurborg S, et al., Generation and characterization of an Advillin-Cre driver mouse line. Mol Pain. 2011;7:66
• All: 39 reference(s)