Kcne3^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Kcne3^{tm1(KOMP)Vlcg}
• Name: potassium voltage-gated channel, Isk-related subfamily, gene 3; targeted mutation 1, Velocigene
• MGI ID: MGI:5292850
• Gene: Kcne3 Location: Chr7:99825714-99834076 bp, + strand Genetic Position: Chr7, 54.33 cM, cytoband F1
• Alliance: Kcne3^{tm1(KOMP)Vlcg} page
• IMPC: Kcne3 gene page

Mutation origin

• Mutant Cell Lines: 10053F-G6, 10053F-G10, 10053F-H8, 10053G-C12, 10053G-F11
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 335bp between positions 99833365-99833699 of Chromosome 7 (Build GRCm39). (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Kcne3 Mutation: 11 strains or lines available

Notes

Mutant cell line 10053F-G10 was used to create mutant mice which demonstrated germline transmission.

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)