Rchy1^tm1.1Raz
Targeted Allele Detail

Summary

• Symbol: Rchy1^tm1.1Raz
• Name: ring finger and CHY zinc finger domain containing 1; targeted mutation 1.1, Razqallah Hakem
• MGI ID: MGI:5293227
• Synonyms: Pirh2^delta2-3
• Gene: Rchy1 Location: Chr5:92096763-92110927 bp, - strand Genetic Position: Chr5, 45.58 cM
• Alliance: Rchy1^tm1.1Raz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175870
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 and 3 were flanked by loxP sites. Cre-mediated recombination removed exons 2 and 3 and the neo cassette. (J:175870)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rchy1 Mutation: 24 strains or lines available

References

• Original: J:175870 Jung YS, et al., Pirh2 e3 ubiquitin ligase monoubiquitinates DNA polymerase eta to suppress translesion DNA synthesis. Mol Cell Biol. 2011 Oct;31(19):3997-4006
• All: 3 reference(s)