Sox9^tm4Tlu
Targeted Allele Detail

Summary

• Symbol: Sox9^tm4Tlu
• Name: SRY (sex determining region Y)-box 9; targeted mutation 4, Thomas Lufkin
• MGI ID: MGI:5293340
• Synonyms: Sox9^floxFRTNeo
• Gene: Sox9 Location: Chr11:112673050-112678586 bp, + strand Genetic Position: Chr11, 77.27 cM
• Alliance: Sox9^tm4Tlu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176950
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 1. An additional loxP site was inserted downstream of exon 1. (J:176950)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sox9 Mutation: 33 strains or lines available

References

• Original: J:176950 Yap SP, et al., Generation of mice with a novel conditional null allele of the Sox9 gene. Biotechnol Lett. 2011 Aug;33(8):1551-8
• All: 1 reference(s)