Pbk^tm1Zgdo
Targeted Allele Detail

Summary

• Symbol: Pbk^tm1Zgdo
• Name: PDZ binding kinase; targeted mutation 1, Zigang Dong
• MGI ID: MGI:5293435
• Gene: Pbk Location: Chr14:66043337-66055271 bp, + strand Genetic Position: Chr14, 34.36 cM
• Alliance: Pbk^tm1Zgdo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176985
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• No details provided. (J:176985)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pbk Mutation: 37 strains or lines available

References

• Original: J:176985 Li S, et al., T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway. J Biol Chem. 2011 Aug 26;286(34):29601-9
• All: 3 reference(s)