Noa1^tm1Tze
Targeted Allele Detail

Summary

• Symbol: Noa1^tm1Tze
• Name: nitric oxide associated 1; targeted mutation 1, Tomasz Zemojtel
• MGI ID: MGI:5293450
• Gene: Noa1 Location: Chr5:77442029-77457931 bp, - strand Genetic Position: Chr5, 41.64 cM
• Alliance: Noa1^tm1Tze page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176798
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of exon 1 was replaced with a floxed neo/kan cassette. The absence of protein expression was confirmed by western blot analysis on E9.5 embryo extracts. (J:176798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Noa1 Mutation: 23 strains or lines available

References

• Original: J:176798 Kolanczyk M, et al., NOA1 is an essential GTPase required for mitochondrial protein synthesis. Mol Biol Cell. 2011 Jan 1;22(1):1-11
• All: 1 reference(s)