Fbxw7^tm1.2Axbe
Targeted Allele Detail

Summary

• Symbol: Fbxw7^tm1.2Axbe
• Name: F-box and WD-40 domain protein 7; targeted mutation 1.2, Axel Behrens
• MGI ID: MGI:5293735
• Synonyms: Fbxw7^delta
• Gene: Fbxw7 Location: Chr3:84722575-84886505 bp, + strand Genetic Position: Chr3, 37.7 cM, cytoband E3.3
• Alliance: Fbxw7^tm1.2Axbe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176598
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the neo cassette from Fbxw7^tm1.1Axbe. (J:176598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbxw7 Mutation: 84 strains or lines available

References

• Original: J:176598 Jandke A, et al., The F-box protein Fbw7 is required for cerebellar development. Dev Biol. 2011 Oct 1;358(1):201-12
• All: 2 reference(s)