Pnpla2^tm1Eek
Targeted Allele Detail

Summary

• Symbol: Pnpla2^tm1Eek
• Name: patatin-like phospholipase domain containing 2; targeted mutation 1, Erin E Kershaw
• MGI ID: MGI:5294351
• Synonyms: ARGL^-, AtglFLOX
• Gene: Pnpla2 Location: Chr7:141035111-141040656 bp, + strand Genetic Position: Chr7, 86.81 cM, cytoband F5
• Alliance: Pnpla2^tm1Eek page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176252
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The gene was flanked with loxP sites. (J:176252)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pnpla2 Mutation: 33 strains or lines available

References

• Original: J:176252 Haemmerle G, et al., ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-alpha and PGC-1. Nat Med. 2011;17(9):1076-85
• All: 45 reference(s)