About   Help   FAQ
Lin28atm1Gqda
Targeted Allele Detail
Summary
Symbol: Lin28atm1Gqda
Name: lin-28 homolog A; targeted mutation 1, George Q Daley
MGI ID: MGI:5294611
Gene: Lin28a  Location: Chr4:133730641-133746152 bp, - strand  Genetic Position: Chr4, 66.5 cM
Alliance: Lin28atm1Gqda page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177113
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 2 via homologous recombination. (J:177113)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Lin28a Mutation:  76 strains or lines available
Notes
The ES cell line used to create this line contained the allele Gt(ROSA)26Sortm1(rtTA*M2)Jae
References
Original:  J:177113 Zhu H, et al., The Lin28/let-7 Axis Regulates Glucose Metabolism. Cell. 2011 Sep 30;147(1):81-94
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory