Liph^tm1Aoki
Targeted Allele Detail

Summary

• Symbol: Liph^tm1Aoki
• Name: lipase, member H; targeted mutation 1, Junken Aoki
• MGI ID: MGI:5294787
• Synonyms: PA-PLA1alpha^-
• Gene: Liph Location: Chr16:21772567-21814408 bp, - strand Genetic Position: Chr16, 12.95 cM, cytoband B1
• Alliance: Liph^tm1Aoki page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177192
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 3 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on stomach extracts. (J:177192)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Liph Mutation: 41 strains or lines available

References

• Original: J:177192 Inoue A, et al., LPA-producing enzyme PA-PLA(1)alpha regulates hair follicle development by modulating EGFR signalling. EMBO J. 2011;30(20):4248-60
• All: 1 reference(s)