Tslp^tm1Mak
Targeted Allele Detail

Summary

• Symbol: Tslp^tm1Mak
• Name: thymic stromal lymphopoietin; targeted mutation 1, Tak Mak
• MGI ID: MGI:5294911
• Gene: Tslp Location: Chr18:32948436-32952850 bp, + strand Genetic Position: Chr18, 18.12 cM
• Alliance: Tslp^tm1Mak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:175844
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An EGFP and neo cassette was inserted into exon 2 five codons after the transcription initiation site. This insertion deletes part of exon 2 and all of exons 3 and 4. (J:175844)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tslp Mutation: 15 strains or lines available

References

• Original: J:175844 Reardon C, et al., Thymic Stromal Lymphopoetin-Induced Expression of the Endogenous Inhibitory Enzyme SLPI Mediates Recovery from Colonic Inflammation. Immunity. 2011 Aug 26;35(2):223-35
• All: 1 reference(s)