Psip1^tm1Eng
Targeted Allele Detail

Summary

• Symbol: Psip1^tm1Eng
• Name: PC4 and SFRS1 interacting protein 1; targeted mutation 1, Alan Engelman
• MGI ID: MGI:5294949
• Gene: Psip1 Location: Chr4:83373917-83404696 bp, - strand Genetic Position: Chr4, 39.46 cM
• Alliance: Psip1^tm1Eng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177408
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 3, and a neomycin resistance (neo) cassette followed by a second loxP site downstream of exon 3 of the PC4 and SFRS1 interacting protein 1 (Psip1) gene. (J:177408)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Psip1 Mutation: 30 strains or lines available

References

• Original: J:177408 Shun MC, et al., LEDGF/p75 functions downstream from preintegration complex formation to effect gene-specific HIV-1 integration. Genes Dev. 2007 Jul 15;21(14):1767-78
• All: 4 reference(s)