Fat3^tm1.2Good
Targeted Allele Detail

Summary

• Symbol: Fat3^tm1.2Good
• Name: FAT atypical cadherin 3; targeted mutation 1.2, Lisa Goodrich
• MGI ID: MGI:5295415
• Gene: Fat3 Location: Chr9:15821485-16412581 bp, - strand Genetic Position: Chr9, 5.16 cM
• Alliance: Fat3^tm1.2Good page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:176668
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Cre-mediated recombination removed exon 23. The FRT-flanked neo cassette remains. The absence of protein expression was confirmed by western blot analysis. (J:176668)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fat3 Mutation: 241 strains or lines available

References

• Original: J:176668 Deans MR, et al., Control of neuronal morphology by the atypical cadherin Fat3. Neuron. 2011 Sep 8;71(5):820-32
• All: 3 reference(s)