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Cd300c2tm1Shib
Targeted Allele Detail
Summary
Symbol: Cd300c2tm1Shib
Name: CD300C molecule 2; targeted mutation 1, Akira Shibuya
MGI ID: MGI:5296504
Synonyms: Cd300d-
Gene: Cd300c2  Location: Chr11:114887595-114892706 bp, - strand  Genetic Position: Chr11, 80.57 cM
Alliance: Cd300c2tm1Shib page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:177613
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMost of exon 1 and all of exon 2 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on spleen extracts. (J:177613)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd300c2 Mutation:  19 strains or lines available
References
Original:  J:177613 Nakano-Yokomizo T, et al., The immunoreceptor adapter protein DAP12 suppresses B lymphocyte-driven adaptive immune responses. J Exp Med. 2011 Aug 1;208(8):1661-71
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory