Crb2^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Crb2^tm1Vlcg
• Name: crumbs family member 2; targeted mutation 1, Velocigene
• MGI ID: MGI:5296808
• Gene: Crb2 Location: Chr2:37666261-37689115 bp, + strand Genetic Position: Chr2, 24.19 cM
• Alliance: Crb2^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177837
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac or C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 - 13 were replaced with an EGFP lox-Ub1- EM7- Neo- lox cassette via homologous recombination. (J:177837)

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crb2 Mutation: 53 strains or lines available

References

• Original: J:177837 Xiao Z, et al., Deficiency in crumbs homolog 2 (Crb2) affects gastrulation and results in embryonic lethality in mice. Dev Dyn. 2011 Dec;240(12):2646-56
• All: 1 reference(s)