Tg(Alb-Nos2)1Mkan
Transgene Detail

Summary

• Symbol: Tg(Alb-Nos2)1Mkan
• Name: transgene insertion 1, Masao Kaneki
• MGI ID: MGI:5296937
• Synonyms: L-iNOS-Tg
• Transgene: Tg(Alb-Nos2)1Mkan Location: unknown
• Alliance: Tg(Alb-Nos2)1Mkan page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Alb-Nos2)1Mkan expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Nos2 (MGI:97361)

• Mutation details: A mouse FLAG- and Myc- tagged Nos2 cDNA was placed under the control of the mouse albumin promoter. The 7.3 kb construct was microinjected into zygotes. Nos2 expression was increased 6.1 fold in this line. Line 2 expression increased 5.2 fold. (J:177591)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:177591 Shinozaki S, et al., Liver-specific inducible nitric-oxide synthase expression is sufficient to cause hepatic insulin resistance and mild hyperglycemia in mice. J Biol Chem. 2011 Oct 7;286(40):34959-75
• All: 1 reference(s)