Tnfsf11^tm1.2Htaka
Targeted Allele Detail

Summary

• Symbol: Tnfsf11^tm1.2Htaka
• Name: tumor necrosis factor (ligand) superfamily, member 11; targeted mutation 1.2, Hiroshi Takayanagi
• MGI ID: MGI:5297062
• Synonyms: Tnfsf11^delta
• Gene: Tnfsf11 Location: Chr14:78514886-78545483 bp, - strand Genetic Position: Chr14, 41.26 cM
• Alliance: Tnfsf11^tm1.2Htaka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177557
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed the neo cassette and exons 3 and 4. (J:177557)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnfsf11 Mutation: 32 strains or lines available

References

• Original: J:177557 Nakashima T, et al., Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med. 2011;17(10):1231-4
• All: 4 reference(s)