Epb41l3tm1.1Jglt
Targeted Allele Detail
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Symbol: |
Epb41l3tm1.1Jglt |
Name: |
erythrocyte membrane protein band 4.1 like 3; targeted mutation 1.1, Jean-Antoine Girault |
MGI ID: |
MGI:5297225 |
Synonyms: |
protein 4.1BKO3 |
Gene: |
Epb41l3 Location: Chr17:69382678-69596984 bp, + strand Genetic Position: Chr17, 40.15 cM
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Alliance: |
Epb41l3tm1.1Jglt page
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Limb clasping and gait abnormalities in Epb41l3tm1.1Jglt/Epb41l3tm1.1Jglt mice
Show the 4 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:177866
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 3. A floxed hygro-GFP cassette was inserted downstream of exon 3. Cre-mediated recombination removed exon 3 and the hygro-GFP cassette. The absence of protein expression was confirmed by western blot analysis on brain and sciatic nerve extract.
(J:177866)
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Generation of the Epb41l3tm1.1Jglt allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Epb41l3 Mutation: |
46 strains or lines available
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Original: |
J:177866 Cifuentes-Diaz C, et al., Protein 4.1B contributes to the organization of peripheral myelinated axons. PLoS One. 2011;6(9):e25043 |
All: |
5 reference(s) |
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