Tg(Aspm-cre/ERT2)1Lmuz
Transgene Detail

Summary

• Symbol: Tg(Aspm-cre/ERT2)1Lmuz
• Name: transgene insertion 1, Luca Muzio
• MGI ID: MGI:5297394
• Synonyms: AspM-CreER^T2
• Transgene: Tg(Aspm-cre/ERT2)1Lmuz Location: unknown
• Alliance: Tg(Aspm-cre/ERT2)1Lmuz page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Aspm-cre/ERT2)1Lmuz expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aspm (MGI:1334448)

• Mutation details: A cre/ERT2-Frt-Kanamycin-Frt sequence was inserted by recombineering methods (in bacterial cells) in the first methionine position of the Aspm gene located in a BAC (BAC RP-24-26-F8). The Kana selection marker was deleted by activation of Flpe in the EL250 E.coli cells. Purified BAC DNA was injected into FVB zygotes. No founder information is available. (J:172348)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aspm (mouse) Summary of all recombinase alleles driven by Aspm. Alliance mouse Aspm gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:172348 Marinaro C, et al., In Vivo Fate Analysis Reveals the Multipotent and Self-Renewal Features of Embryonic AspM Expressing Cells. PLoS One. 2011;6(4):e19419
• All: 3 reference(s)