Il17c^tm1.1Cdon
Targeted Allele Detail

Summary

• Symbol: Il17c^tm1.1Cdon
• Name: interleukin 17C; targeted mutation 1.1, Chen Dong
• MGI ID: MGI:5297496
• Gene: Il17c Location: Chr8:123148759-123150378 bp, + strand Genetic Position: Chr8, 71.03 cM
• Alliance: Il17c^tm1.1Cdon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177650
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ gene and floxed puro cassette was inserted downstream of exon 1. Cre-mediated recombination removed the neo cassette. (J:177650)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il17c Mutation: 10 strains or lines available

References

• Original: J:177650 Chang SH, et al., Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E. Immunity. 2011 Oct 28;35(4):611-21
• All: 2 reference(s)